Recombinant Human IKB beta protein (ab123184)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MGSHMAGVAC LGKAADADEW CDSGLGSLGP DAAAPGGPGL GAELGPGLSW APLVFGYVTE DGDTALHLAV IHQHEPFLDF LLGFSAGTEY MDLQNDLGQT ALHLAAILGE TSTVEKLYAA GAGLCVAERR GHTALHLACR VGAHACARAL LQPRPRRPRE APDTYLAQGP DRTPDTNHTP VALYPDSDLE KEEEESEEDW KLQLEAENYE GHTPLHVAVI HKDVEMVRLL RDAGADLDKP EPTCGRSPLH LAVEAQAADV LELLLRAGAN PAARMYGGRT PLGSAMLRPN PILARLLRAH GAPEPEGEDE KSGPCSSSSD SDSGDEGDEY DDIVVHSSRS QTRLPPTPAS KPLPDDPRPV
    • 分子量
      40 kDa including tags
    • 領域
      1 to 356
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab123184 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol

関連情報

  • 別名
    • I kappa B beta
    • I-kappa-B-beta
    • IkappaBbeta
    • IKB beta
    • IkB-B
    • IkB-beta
    • IKBB
    • IKBB_HUMAN
    • IkBbeta
    • NF kappa BIB
    • NF-kappa-B inhibitor beta
    • NF-kappa-BIB
    • Nfkbib
    • Thyroid receptor interacting protein 9
    • Thyroid receptor-interacting protein 9
    • TR interacting protein 9
    • TR-interacting protein 9
    • TRIP-9
    • TRIP9
    see all
  • 機能
    Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
  • 組織特異性
    Expressed in all tissues examined.
  • 配列類似性
    Belongs to the NF-kappa-B inhibitor family.
    Contains 6 ANK repeats.
  • 翻訳後修飾
    Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.
  • 細胞内局在
    Cytoplasm. Nucleus.
  • Information by UniProt

Recombinant Human IKB beta protein 画像

  • 15% SDS-PAGE showing ab123184 at approximately 40.3kDa (3µg).
    (Molecular size on SDS-PAGE will appear higher).

Recombinant Human IKB beta protein (ab123184) 使用論文

ab123184 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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