Recombinant human IGFBP2 protein (ab63223)

製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Insect cells
  • アミノ酸配列
    • アクセッション番号P18065
    • 生物種Human
    • 配列EVLFRCPPCT PERLAACGPP PVAPPAAVAA VAGGARMPCA ELVREPGCGC CSVCARLEGE ACQVYTPRCG QGLRCYPHPG SELPLQALVM GEGTCEKRRD AEYGASPEQV ADNGDDHSEG GLVENHVDST MNMLGGGGSA GRKPLKSGMK ELAVFREKVT EQHRQMGKGG KHHLGLEEPK KLRPPPARTP CQQELDQVLE RISTMRLPDE RGPLEHLYSL HIPNCDKHGL YNLKQCKMSL NGQRGECWCV NPNTGKLIQG APTIRGDPEC HLFYNEQQEA RGVHTQRMQ
    • 分子量32 kDa
    • 領域37 to 325
    • 配列の追加情報The sequence is the full length mature form minus the signal peptide.

特性

Our Abpromise guarantee covers the use of ab63223 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Biological Activity : Determined by its ability to inhibit IGF-I induced proliferation of FDC-P1 cells.

  • アプリケーション

    Western blot

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル< 1.000 Eu/µg
  • 精製度> 98 % SDS-PAGE.
    Greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is < 0.1 ng/µg of protein (<1EU/µg).
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • BP 2
    • BP2
    • IBP 2
    • IBP-2
    • IBP2
    • IBP2_HUMAN
    • IGF binding protein 2
    • IGF BP53
    • IGF-binding protein 2
    • IGFBP 2
    • IGFBP-2
    • IGFBP2
    • IGFBP53
    • Insulin like growth factor binding protein 2
    • Insulin like growth factor binding protein 2 36kDa
    • Insulin like growth factor-binding protein 2 precursor
    • Insulin-like growth factor-binding protein 2
    see all
  • 機能Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
  • 配列類似性Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • ドメインThe C-terminus is required for IGF-binding and growth inhibition.
  • 翻訳後修飾O-glycosylated.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human IGFBP2 protein 画像

  • Anti-IGFBP2 antibody (ab91404) at 1/500 dilution + Recombinant human IGFBP2 protein (ab63223) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

Recombinant human IGFBP2 protein (ab63223) 使用論文

ab63223 has not yet been referenced specifically in any publications.

Product Wall

A serum-free media is used for culturing. However, please note that the virus stock contains serum and the final concentration of the serum is 0.1% FBS in the production.

This product is provided is free of any carrier proteins.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"