製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NCNKNGFYHS RQCETSMDGE AGLCWCVYPW NGKRIPGSPE IRGDPNCQIY FNVQN

特性

Our Abpromise guarantee covers the use of ab50216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Biological Activity : The ED50, as determined by its ability to inhibit IGF-I induced proliferation of MCF-7, is < 0.5 µg/ml in the presence of 6 ng/ml of human IGF-I.
  • アプリケーション

    Western blot

    SDS-PAGE

    Functional Studies

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Reconsitute to 1mg/ml with sterile water.

関連情報

  • 別名
    • AFBP
    • Alpha pregnancy associated endometrial globulin
    • Amniotic fluid binding protein
    • Binding protein 25
    • Binding protein 26
    • Binding protein 28
    • Growth hormone independent binding protein
    • hIGFBP 1
    • hIGFBP1
    • IBP 1
    • IBP-1
    • IBP1
    • IBP1_HUMAN
    • IGF binding protein 1
    • IGF BP25
    • IGF-binding protein 1
    • IGFBP 1
    • IGFBP-1
    • IGFBP1
    • Insulin like growth factor binding protein 1
    • Insulin-like growth factor-binding protein 1
    • Placental protein 12
    • PP 12
    • PP12
    see all
  • 機能IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
  • 配列類似性Contains 1 IGFBP N-terminal domain.
    Contains 1 thyroglobulin type-1 domain.
  • 翻訳後修飾Phosphorylated; probably by casein kinase II. Alters the affinity of the protein for IGFs.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human IGFBP1 protein 画像

  • Anti-IGFBP1 antibody [33627.11] (ab94985) at 1 µg/ml + Recombinant human IGFBP1 protein (ab50216) at 0.1 µg

    Secondary
    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

Recombinant human IGFBP1 protein (ab50216) 使用論文

ab50216 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"