製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O00273
    • 生物種Human
    • 分子量38 kDa
    • 領域1 to 331
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab124317 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Preservative: 0.88% Imidazole
    Constituents: 1.75% Sodium chloride, 0.6% Monobasic dihydrogen sodium phosphate

関連情報

  • 別名
    • A330085O09Rik
    • Caspase activated deoxyribonuclease inhibitor short form
    • DFF 1
    • DFF 45
    • DFF alpha
    • DFF-45
    • DFF1
    • DFF35
    • DFF45
    • DFFA
    • Dffa DNA fragmentation factor, alpha subunit
    • DFFA_HUMAN
    • DNA fragmentation factor 45 kDa subunit
    • DNA Fragmentation Factor Alpha Subunit
    • DNA fragmentation factor subunit alpha
    • DNA fragmentation factor, 45 kD, alpha subunit
    • DNA fragmentation factor, 45kDa, alpha polypeptide
    • DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1
    • DNA fragmentation factor, alpha subunit
    • DNAation factor 45 kDa subunit
    • H13
    • ICAD
    • ICAD L
    • ICAD S
    • Inhibitor of CAD
    • Inhibitor of Caspase Activated DNase
    • MGC143066
    • OTTHUMP00000001903
    • OTTHUMP00000001904
    • RP23 121D17.3
    see all
  • 機能Inhibitor of the caspase-activated DNase (DFF40).
  • 配列類似性Contains 1 CIDE-N domain.
  • 翻訳後修飾Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human ICAD protein 画像

  • SDS-PAGE using 1µg of ab124317.

Recombinant Human ICAD protein (ab124317) 使用論文

ab124317 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"