Recombinant Human Hsd17b11 protein (ab101826)

製品の概要

  • 製品名
    Recombinant Human Hsd17b11 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMESFVKLFIPKRRKSVTGEIVLITGAGHGI GRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNRE DIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAH FWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKT LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMH GILTEQKMIFIPSSIAFLTTLERILPERFLAVLKQKI
    • 分子量
      31 kDa including tags
    • 領域
      20 to 285
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab101826 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab101826 was purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, pH 8.0

関連情報

  • 別名
    • 17 beta HSD 11
    • 17 beta HSD XI
    • 17 BETA HSD11
    • 17 BETA HSDXI
    • 17 beta hydroxysteroid dehydrogenase 11
    • 17 beta hydroxysteroid dehydrogenase type XI
    • 17 beta hydroxysteroid dehydrogenase XI
    • 17-beta-HSD 11
    • 17-beta-HSD XI
    • 17-beta-hydroxysteroid dehydrogenase 11
    • 17-beta-hydroxysteroid dehydrogenase XI
    • 17betaHSD11
    • 17betaHSDXI
    • 17bHSD11
    • CTCL associated antigen HD CL 03
    • CTCL tumor antigen HD CL 03
    • CTCL-associated antigen HD-CL-03
    • Cutaneous T cell lymphoma associated antigen HD CL 03
    • Cutaneous T-cell lymphoma-associated antigen HD-CL-03
    • Dehydrogenase/reductase SDR family member 8
    • DHB11_HUMAN
    • DHRS8
    • Estradiol 17 beta dehydrogenase 11
    • Estradiol 17-beta-dehydrogenase 11
    • Hsd17b11
    • Hydroxysteroid (17 beta) dehydrogenase 11
    • PAN1B
    • Retinal short chain dehydrogenase/reductase 2
    • Retinal short-chain dehydrogenase/reductase 2
    • RETSDR2
    • SDR16C2
    • SDR2
    • Short chain dehydrogenase/reductase family 16C member 2
    • T cell lymphoma associated antigen HD CL 03
    see all
  • 機能
    Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
  • 組織特異性
    Present at high level in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells, and granulosa cells of the dominant follicle and corpus luteum. In lung, it is detected in the ciliated epithelium and in acini of adult trachea, in bronchioles, but not in alveoli. In the eye, it is detected in the nonpigmented epithelium of the ciliary body and, at lower level, in the inner nuclear layer of the retina (at protein level). Widely expressed. Highly expressed in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart.
  • 配列類似性
    Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
  • 細胞内局在
    Secreted.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of 3µg ab101826

参考文献

ab101826 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab101826.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録