Recombinant Human hnRNP A1 protein (ab123212)

製品の概要

  • 製品名Recombinant Human hnRNP A1 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P09651-2
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGSMSKSESP KEPEQLRKLF IGGLSFETTD ESLRSHFEQW GTLTDCVVMR DPNTKRSRGF GFVTYATVEE VDAAMNARPH KVDGRVVEPK RAVSREDSQR PGAHLTVKKI FVGGIKEDTE EHHLRDYFEQ YGKIEVIEIM TDRGSGKKRG FAFVTFDDHD SVDKIVIQKY HTVNGHNCEV RKALSKQEMA SASSSQRGRS GSGNFGGGRG GGFGGNDNFG RGGNFSGRGG FGGSRGGGGY GGSGDGYNGF GNDGSNFGGG GSYNDFGNYN NQSSNFGPMK GGNFGGRSSG PYGGGGQYFA KPRNQGGYGG SSSSSSYGSG RRF
    • 分子量37 kDa including tags
    • 領域1 to 320
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度> 85 % SDS-PAGE.
    ab123212 was purified using conventional chromatography and is > 85% pure by SDS - PAGE.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 40% Glycerol, 0.88% Sodium chloride

関連情報

  • 別名
    • HNRNPA 1
    • Helix destabilizing protein
    • Helix-destabilizing protein
    • Heterogeneous nuclear ribonucleoprotein A1
    • Heterogeneous nuclear ribonucleoprotein A1B protein
    • Heterogeneous nuclear ribonucleoprotein B2 protein
    • Heterogeneous nuclear ribonucleoprotein core protein A1
    • hnRNP A1
    • hnRNP core protein A1
    • HNRNPA1
    • HNRPA1
    • MGC102835
    • Nuclear ribonucleoprotein particle A1 protein
    • ROA1_HUMAN
    • Single strand DNA binding protein UP1
    • Single strand RNA binding protein
    • Single-strand RNA-binding protein
    see all
  • 機能Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.
  • 配列類似性Contains 2 RRM (RNA recognition motif) domains.
  • 翻訳後修飾Arg-194, Arg-206 and Arg-225 are dimethylated, probably to asymmetric dimethylarginine.
    Sumoylated.
  • 細胞内局在Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Shuttles continuously between the nucleus and the cytoplasm along with mRNA. Component of ribonucleosomes. In the course of viral infection, colocalizes with HCV NS5B at speckles in the cytoplasm in a HCV-replication dependent manner.
  • Information by UniProt

Recombinant Human hnRNP A1 protein 画像

  • 15% SDS-PAGE analysis of ab123212 (3 µg)

Recombinant Human hnRNP A1 protein (ab123212) 使用論文

ab123212 has not yet been referenced specifically in any publications.

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Regrettably, the biological activity of this product has not yet been tested. Although it is scheduled to be tested eventually, we can’t give you a specific date on when we will have the results.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"