Recombinant Human HEXIM1 protein (ab117163)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O94992
    • 生物種Human
    • 配列MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAE PFLSEYQHQP QTSNCTGAAA VQEELNPERP PGAEERVPEE DSRWQSRAFP QLGGRPGPEG EGSLESQPPP LQTQACPESS CLREGEKGQN GDDSSAGGDF PPPAEVEPTP EAELLAQPCH DSEASKLGAP AAGGEEEWGQ QQRQLGKKKH RRRPSKKKRH WKPYYKLTWE EKKKFDEKQS LRASRIRAEM FAKGQPVAPY NTTQFLMDDH DQEEPDLKTG LYSKRAAAKS DDTSDDDFME EGGEEDGGSD GMGGDGSEFL QRDFSETYER YHTESLQNMS KQELIKEYLE LEKCLSRMED ENNRLRLESK RLGGDDARVR ELELELDRLR AENLQLLTEN ELHRQQERAP LSKFGD
    • 分子量45 kDa including tags
    • 領域1 to 359
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab117163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 90 % SDS-PAGE.
    ab117163 was purified by proprietary chromatographic techniques and filter sterilized.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.58% Sodium chloride, 10% Glycerol, 0.32% Tris HCl

関連情報

  • 別名
    • Cardiac lineage protein 1
    • CLP 1
    • CLP1
    • EDG 1
    • EDG1
    • Estrogen down-regulated gene 1 protein
    • FLJ13562
    • Hexamethylene bis acetamide inducible 1
    • Hexamethylene bis acetamide inducible protein
    • Hexamethylene bis acetamide inducible transcript 1
    • Hexamethylene bis-acetamide-inducible protein 1
    • HEXI1_HUMAN
    • HEXIM 1
    • Hexim1
    • HEXIM1 protein
    • HIS 1
    • HIS1
    • HMBA inducible
    • MAQ 1
    • MAQ1
    • Menage a quatre 1
    • Menage a quatre protein 1
    • Protein HEXIM1
    see all
  • 機能Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
  • 組織特異性Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues.
  • 配列類似性Belongs to the HEXIM family.
  • ドメインThe coiled-coil domain mediates oligomerization.
  • 細胞内局在Nucleus. Cytoplasm. Binds alpha-importin and is mostly nuclear.
  • Information by UniProt

Recombinant Human HEXIM1 protein (ab117163) 使用論文

ab117163 has not yet been referenced specifically in any publications.

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