製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMLPRLICINDYEQH AKSVLPKSIYDYYRSGAN DEETLADNIAAFSRWKLYPRMLRNVAETDL STSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMML SSW ATSSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVD TPYLGNRLDDVRNRFKLPPQLR MKNFETSTLSFSPEENFGDDSGLAAY VAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILV SNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALAL GAKAVFVGRPIVWGLAFQGEKGVQDV LEILKEEFRLAMALSGCQNVKV IDKTLVRKNPLAVSKI
    • 分子量
      45 kDa including tags
    • 領域
      1 to 370
    • タグ
      His tag N-Terminus , DDDDK tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113144 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab113144 was purified using conventional chromatography.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 2.92% Sodium chloride

関連情報

  • 別名
    • (S) 2 hydroxy acid oxidase
    • Glycolate oxidase
    • GOX
    • GOX1
    • HAO1
    • HAOX1
    • HAOX1_HUMAN
    • Hydroxyacid oxidase 1
    • MGC142225
    • MGC142227
    • OTTHUMP00000030231
    see all
  • 機能
    Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate.
  • 組織特異性
    Liver.
  • パスウェイ
    Organic acid metabolism; glycolate degradation; 3-phospho-D-glycerate from glycolate: step 1/4.
  • 配列類似性
    Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
    Contains 1 FMN hydroxy acid dehydrogenase domain.
  • 細胞内局在
    Peroxisome.
  • Information by UniProt

Recombinant Human HAO1 protein 画像

  • 15% SDS-PAGE analysis of ab113144 (3µg)

Recombinant Human HAO1 protein (ab113144) 使用論文

This product has been referenced in:
  • Wang M  et al. High throughput cell-based assay for identification of glycolate oxidase inhibitors as a potential treatment for Primary Hyperoxaluria Type 1. Sci Rep 6:34060 (2016). Read more (PubMed: 27670739) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab113144.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録