製品の概要
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製品名Recombinant Human GRHPR protein
GRHPR タンパク質・ペプチド 製品一覧 -
タンパク質長Full length protein
製品の詳細
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由来Recombinant
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由来Escherichia coli
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アミノ酸配列
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アクセッション番号
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生物種Human
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配列MGSSHHHHHH SSGLVPRGSH MRPVRLMKVF VTRRIPAEGR VALARAADCE VEQWDSDEPI PAKELERGVA GAHGLLCLLS DHVDKRILDA AGANLKVIST MSVGIDHLAL DEIKKRGIRV GYTPDVLTDT TAELAVSLLL TTCRRLPEAI EEVKNGGWTS WKPLWLCGYG LTQSTVGIIG LGRIGQAIAR RLKPFGVQRF LYTGRQPRPE EAAEFQAEFV STPELAAQSD FIVVACSLTP ATEGLCNKDF FQKMKETAVF INISRGDVVN QDDLYQALAS GKIAAAGLDV TSPEPLPTNH PLLTLKNCVI LPHIGSATHR TRNTMSLLAA NNLLAGLRGE PMPSELKL
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分子量38 kDa including tags
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領域1 to 328
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タグHis tag N-Terminus
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関連製品
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Related Products
特性
Our Abpromise guarantee covers the use of ab119159 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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精製度> 95 % SDS-PAGE.
ab119159 is purified by proprietary chromatographic techniques. -
製品の状態Liquid
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備考Please prevent freeze thaw cycles.
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -20°C. Store under desiccating conditions.
pH: 8.00
Constituents: 0.32% Tris HCl, 1.17% Sodium chloride, 0.08% DTT, 20% Glycerol
関連情報
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別名
- GLXR
- glycerate 2 dehydrogenase
- GLYD
see all -
機能Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
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組織特異性Ubiquitous. Most abundantly expressed in the liver.
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関連疾患Defects in GRHPR are the cause of hyperoxaluria primary type 2 (HP2) [MIM:260000]; also known as primary hyperoxaluria type II (PH2). HP2 is a disorder where the main clinical manifestation is calcium oxalate nephrolithiasis though chronic as well as terminal renal insufficiency has been described. It is characterized by an elevated urinary excretion of oxalate and L-glycerate.
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配列類似性Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
- Information by UniProt
Recombinant Human GRHPR protein (ab119159) 使用論文
ab119159 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"