Recombinant Human GRASP65 protein (ab112424)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q9BQQ3
    • 生物種Human
    • 配列MGLGVSAEQPAGGAEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNK ENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASV RFCSFRRASEQVWHVLDVEPSSPAALAGLRPYTDYVVGSDQILQESEDFF TLIESHEGKPLKLMVYNSKSDSCREVTVTPNAAWGGEGSLGCGIGYGYLH RIPTQPPSYHKKPPGTPPPSALPLGAPPPDALPPGPTPEDSPSLETGSRQ SDYMEALLQAPGSSMEDPLPGPGSPSHSAPDPDGLPHFMETPLQPPPPVQ RVMDPGFLDVSGISLLDNSNASVWPSLPSSTELTTTAVSTSGPEDICSSS SSHERGGEATWSGSEFEVSFLDSPGAQAQADHLPQLTLPDSLTSAASPED GLSAELLEAQAEEEPASTEGLDTGTEAEGLDSQAQISTTE
    • 分子量74 kDa including tags
    • 領域1 to 440

関連製品

特性

Our Abpromise guarantee covers the use of ab112424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    ELISA

    Western blot

  • 製品の状態Liquid
  • 備考Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

関連情報

  • 別名
    • FLJ23443
    • Golgi peripheral membrane protein p65
    • Golgi phosphoprotein 5
    • Golgi reassembly and stacking protein 1
    • Golgi reassembly and stacking protein 65 kDa
    • Golgi reassembly and stacking protein, 65-kD
    • Golgi reassembly stacking protein 1
    • Golgi reassembly stacking protein 1 65kDa
    • Golgi reassembly stacking protein of 65 kDa
    • Golgi reassembly-stacking protein 1
    • Golgi reassembly-stacking protein of 65 kDa
    • GOLPH 5
    • GOLPH5
    • Gorasp 1
    • GORASP1
    • GORS1_HUMAN
    • GRASP 65
    • GRASP65
    • MGC118894
    • MGC118897
    • P65
    see all
  • 機能Stacking factor involved in the postmitotic assembly of Golgi stacks from mitotic Golgi fragments. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis. Also mediates, via its interaction with GM130, the docking of transport vesicles with the Golgi membranes.
  • 配列類似性Belongs to the GORASP family.
    Contains 1 PDZ (DHR) domain.
  • 翻訳後修飾Phosphorylated by CDC2/B1 and PLK kinases during mitosis. Phosphorylation cycle correlates with the cisternal stacking cycle. Phosphorylation of the homodimer prevents the association of dimers into higher order oligomers, leading to cisternal unstacking.
    Target for caspase-3 cleavage during apoptosis. The cleavage contributes to Golgi fragmentation and occurs very early in the execution phase of apoptosis.
  • 細胞内局在Golgi apparatus > cis-Golgi network membrane. Undergoes rapid exchange with the cytosol.
  • Information by UniProt

Recombinant Human GRASP65 protein 画像

  • ab112424 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

Recombinant Human GRASP65 protein (ab112424) 使用論文

ab112424 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"