Recombinant Human Glutaredoxin 5 protein (ab95352)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MSGSLGRAAA ALLRWGRGAG GGGLWGPGVR AAGSGAGGGG SAEQLDALVK KDKVVVFLKG TPEQPQCGFS NAVVQILRLH GVRDYAAYNV LDDPELRQGI KDYSNWPTIP QVYLNGEFVG GCDILLQMHQ NGDLVEELKK LGIHSALLDE KKDQDSK

特性

Our Abpromise guarantee covers the use of ab95352 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0

関連情報

  • 別名
    • C14orf87
    • Chromosome 14 open reading frame 87
    • FLB4739
    • GLRX 5
    • Glrx5
    • GLRX5_HUMAN
    • Glutaredoxin 5 homolog
    • Glutaredoxin related protein 5
    • Glutaredoxin-related protein 5
    • Glutaredoxin5
    • GRX5
    • MGC14129
    • mitochondrial
    • Monothiol glutaredoxin-5
    • PRO1238
    see all
  • 機能Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.
  • 関連疾患Defects in GLRX5 are a cause of anemia sideroblastic pyridoxine-refractory autosomal recessive (PRARSA) [MIM:205950]. A form of sideroblastic anemia not responsive to pyridoxine. Sideroblastic anemia is characterized by anemia of varying severity, hypochromic peripheral erythrocytes, systemic iron overload secondary to chronic ineffective erythropoiesis, and the presence of bone marrow ringed sideroblasts. Sideroblasts are characterized by iron-loaded mitochondria clustered around the nucleus.
  • 配列類似性Belongs to the glutaredoxin family. Monothiol subfamily.
    Contains 1 glutaredoxin domain.
  • 細胞内局在Mitochondrion.
  • Information by UniProt

Recombinant Human Glutaredoxin 5 protein 画像

  • 15% SDS-PAGE showing ab95352 at approximately 19 kDa (3 µg).

Recombinant Human Glutaredoxin 5 protein (ab95352) 使用論文

ab95352 has not yet been referenced specifically in any publications.

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