Recombinant Human Glutamyl hydrolase gamma protein (ab123172)

製品の概要

  • 製品名
    Recombinant Human Glutamyl hydrolase gamma protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMRPHGDTAKKPIIGILMQKCRNKVMKNYGR YYIAASYVKYLESAGARVVPVRLDLTEKDYEILFKSINGILFPGGSVDLR RSDYAKVAKIFYNLSIQSFDDGDYFPVWGTCLGFEELSLLISGECLLTAT DTVDVAMPLNFTGGQLHSRMFQNFPTELLLSLAVEPLTANFHKWSLSVKN FTMNEKLKKFFNVLTTNTDGKIEFISTMEGYKYPVYGVQWHPEKAPYEWK NLDGISHAPNAVKTAFYLAEFFVNEARKNNHHFKSESEEEKALIYQFSPI YTGNISSFQQCYIFD
    • 分子量
      36 kDa including tags
    • 領域
      25 to 318
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    ab123172 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

関連情報

  • 別名
    • Conjugase
    • folylpolygammaglutamyl hydrolase
    • gamma glutamyl hydrolase
    • Gamma-Glu-X carboxypeptidase
    • Gamma-glutamyl hydrolase
    • Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
    • GGH
    • GGH_HUMAN
    • gH
    see all
  • 機能
    Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
  • 配列類似性
    Belongs to the peptidase C26 family.
    Contains 1 gamma-glutamyl hydrolase domain.
  • 細胞内局在
    Secreted > extracellular space. Lysosome. Melanosome. While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab123172 at approximately 35.9 kDa (3µg loaded).

参考文献

ab123172 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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