製品の概要

  • 製品名
    Recombinant Human GHRHR protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      HMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGE WVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEE ESYFSTVKII
    • 分子量
      38 kDa including tags
    • 領域
      23 to 132

特性

Our Abpromise guarantee covers the use of ab114388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

    SDS-PAGE

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    ab114388 is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • GHRFR
    • GHRH R
    • GHRH receptor
    • Ghrhr
    • GHRHR_HUMAN
    • GHRHRpsv
    • GRF R
    • GRF receptor
    • GRFR
    • Growth hormone releasing factor receptor
    • Growth hormone releasing hormone receptor
    • Growth hormone-releasing factor receptor
    • Growth hormone-releasing hormone receptor
    see all
  • 機能
    Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
  • 組織特異性
    Pituitary gland.
  • 関連疾患
    Defects in GHRHR are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH.
  • 配列類似性
    Belongs to the G-protein coupled receptor 2 family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt

画像

  • ab114388 analysed on a 12.5% SDS-PAGE Stained with Coomassie Blue.

参考文献

ab114388 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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