由来 Escherichia coli
配列 MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMNPS MKQKQEEIKE NIKNSSVPRR TLKMIQPSAS GSLVGRENEL SAGLSKRKHR NDHLTSTTSS PGVIVPESSE NKNLGGVTQE SFDLMIKENP SSQYWKEVAE KRRKALYEAL KENEKLHKEI EQKDNEIARL KKENKELAEV AEHVQYMAEL IERLNGEPLD NFESLDNQEF DSEEETVEDS LVEDSEIGTC AEGTVSSSTD AKPCI 特性
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
精製度 > 95
% SDS-PAGE. ab86447 is purified using conventional chromatography techniques.
Concentration information loading... 前処理および保存
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris, 100mM Sodium chloride, pH 8.0
DNA replication inhibitor
機能 Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle.
配列類似性 Belongs to the geminin family.
発生段階 Absent during G1 phase, accumulates during S, G2, and M phases, and disappears at the time of the metaphase-anaphase transition.
Information by UniProt
Recombinant Human Geminin protein 画像
Recombinant Human Geminin protein (ab86447) 使用論文
has not yet been referenced specifically in any publications.
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