Recombinant human GDF15 protein (ab50077)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Mammalian
  • アミノ酸配列
    • アクセッション番号Q99988
    • 生物種Human
    • 配列ARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPS QFRAANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMVLIQKTDTGVSLQT YDDLLAKDCHCI
    • 領域197 to 308
    • 配列の追加情報This product refers to the processed mature form of this protein from aa 195 to 308. Therefore it does not contain the signal peptide or propeptide.

特性

Our Abpromise guarantee covers the use of ab50077 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Determined by its ability to inhibit alkaline phosphatase activity in differentiating MC3T3/E1 osetoblast cells. The expected ED50 for this effect is 1.0-3.0 μg/ml.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル< 1.000 Eu/µg
  • 精製度> 98 % SDS-PAGE.
    ab50077 purity was determined also by HPLC Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Reconstitute to 1mg/ml with distilled water.

関連情報

  • 別名
    • GDF 15
    • GDF-15
    • Gdf15
    • GDF15_HUMAN
    • Growth differentiation factor 15
    • Growth/differentiation factor 15
    • Macrophage inhibitory cytokine 1
    • MIC 1
    • Mic-1
    • MIC1
    • NAG 1
    • NAG-1
    • NAG1
    • NRG 1
    • NRG-1
    • NRG1
    • NSAID
    • NSAID (nonsteroidal anti inflammatory drug) activated protein 1
    • NSAID regulated protein 1
    • NSAID-activated gene 1 protein
    • NSAID-regulated gene 1 protein
    • PDF
    • PLAB
    • Placental bone morphogenetic protein
    • Placental bone morphogenic protein
    • Placental TGF beta
    • Placental TGF-beta
    • Prostate differentiation factor
    • PTGF beta
    • PTGFB
    see all
  • 組織特異性Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
  • 配列類似性Belongs to the TGF-beta family.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human GDF15 protein (ab50077) 使用論文

ab50077 has not yet been referenced specifically in any publications.

Product Wall

I have received from the lab further information about ab50077. This product was lyophilized from 10 mM Sodium Citrate, pH 3.0.

I can confirm that the GDF15 protein ab50077 is naturally secreted by a proprietary cell line and then purified. No recombinant techniques are involved in the production of this protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"