製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q99988
    • 生物種Human
    • 配列MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI
    • 領域197 to 308
    • 配列の追加情報This product refers to the processed mature form of this protein from aa 195 to 308. The signal peptide and propeptide are removed.

特性

Our Abpromise guarantee covers the use of ab125769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性The activity is determined by the inhibition of DU-145 cells and is typically 1-2 (g/mL).
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • エンドトキシン・レベル< 0.100 Eu/µg
  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • 備考Lyophilized product is very stable at -20°C. Reconstituted material should be aliquoted and frozen at -20°C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Centrifuge vial before opening. It is recommended to reconstitute the lyophilized product with sterile 5 mM acetic acid at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.

関連情報

  • 別名
    • GDF 15
    • GDF-15
    • Gdf15
    • GDF15_HUMAN
    • Growth differentiation factor 15
    • Growth/differentiation factor 15
    • Macrophage inhibitory cytokine 1
    • MIC 1
    • Mic-1
    • MIC1
    • NAG 1
    • NAG-1
    • NAG1
    • NRG 1
    • NRG-1
    • NRG1
    • NSAID
    • NSAID (nonsteroidal anti inflammatory drug) activated protein 1
    • NSAID regulated protein 1
    • NSAID-activated gene 1 protein
    • NSAID-regulated gene 1 protein
    • PDF
    • PLAB
    • Placental bone morphogenetic protein
    • Placental bone morphogenic protein
    • Placental TGF beta
    • Placental TGF-beta
    • Prostate differentiation factor
    • PTGF beta
    • PTGFB
    see all
  • 組織特異性Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
  • 配列類似性Belongs to the TGF-beta family.
  • 細胞内局在Secreted.
  • Information by UniProt

Recombinant human GDF15 protein (ab125769) 使用論文

ab125769 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"