製品の概要

  • 製品名Recombinant Human GCDH protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q92947
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMRPEFDWQDPLVLEEQLTTDEILIRDTFRT YCQERLMPRILLANRNEVFHREIISEMGELGVLGPTIKGYGCAGVSSVAY GLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKGEL LGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFV VWARCEDGCIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPE ENVLPGASSLGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFG VPLARNQLIQKKLADMLTEITLGLHACLQLGRLKDQDKAAPEMVSLLKRN NCGKALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALI LGRAITGIQAFTASK
    • 分子量46 kDa including tags
    • 領域45 to 438
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab98118 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab98118 is purified by using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 5mM DTT, 200mM Sodium chloride, 20mM Tris HCl, pH 8

関連情報

  • 別名
    • ACAD5
    • EC 1.3.99.7
    • GCD
    • Gcdh
    • GCDH_HUMAN
    • Glutaryl CoA dehydrogenase
    • Glutaryl CoA dehydrogenase, mitochondrial
    • Glutaryl Coenzyme A dehydrogenase
    • Glutaryl-CoA dehydrogenase
    • mitochondrial
    • MS781
    see all
  • 機能Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive.
  • 組織特異性Isoform 1 and isoform 2 are expressed in fibroblasts and liver.
  • パスウェイAmino-acid metabolism; lysine degradation.
    Amino-acid metabolism; tryptophan metabolism.
  • 関連疾患Defects in GCDH are the cause of glutaric aciduria type 1 (GA1) [MIM:231670]. GA1 is an autosomal recessive metabolic disorder characterized by progressive dystonia and athetosis due to gliosis and neuronal loss in the basal ganglia.
  • 配列類似性Belongs to the acyl-CoA dehydrogenase family.
  • 細胞内局在Mitochondrion matrix.
  • Information by UniProt

Recombinant Human GCDH protein 画像

  • 15% SDS-PAGE analysis of ab98118 (3µg)

Recombinant Human GCDH protein (ab98118) 使用論文

ab98118 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab98118.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"