製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号O14976
    • 生物種Human
    • 配列SAVAPTPATEGPLFSPGGQPAPCGSQASWTKSQNPDPFADLGDLSSGLQG SPAGFPPGGFIPKTATTPKGSSSWQTSRPPAQGASWPPQAKPPPKACTQP
    • 分子量37 kDa including tags
    • 領域151 to 250

特性

Our Abpromise guarantee covers the use of ab114800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Auxilin 2
    • Cyclin G associated kinase
    • Cyclin-G-associated kinase
    • DNAJ26
    • DNAJC26
    • EC 2.7.11.1
    • FLJ16629
    • FLJ40395
    • GAK
    • GAK protein
    • GAK_HUMAN
    • MGC99654
    see all
  • 機能Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
  • 組織特異性Ubiquitous. Highest in testis.
  • 配列類似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 C2 tensin-type domain.
    Contains 1 J domain.
    Contains 1 phosphatase tensin-type domain.
    Contains 1 protein kinase domain.
  • 細胞内局在Cytoplasm > perinuclear region. Golgi apparatus > trans-Golgi network. Cell junction > focal adhesion. Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focals adhesions.
  • Information by UniProt

Recombinant Human GAK protein 画像

  • ab114800 on 12.5% SDS-PAGE Stained with Coomassie Blue.

Recombinant Human GAK protein (ab114800) 使用論文

ab114800 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114800.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"