Recombinant Human GADD45GIP1 protein (ab113863)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q8TAE8
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMPRWQLGPRYAAKQFARYGAASGVVPGSLW PSPEQLRELEAEEREWYPSLATMQESLRVKQLAEEQKRREREQHIAECMA KMPQMIVNWQQQQRENWEKAQADKERRARLQAEAQELLGYQVDPRSARFQ ELLQDLEKKERKRLKEEKQKRKKEARAAALAAAVAQDPAASGAPSS
    • 分子量23 kDa including tags
    • 領域48 to 222
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab113863 was purified by using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 40% Glycerol, 0.03% DTT, 1.17% Sodium chloride

関連情報

  • 別名
    • 39S ribosomal protein L59 mitochondrial
    • CKBBP2
    • CKbetaBP2
    • CKII beta associating protein
    • CKII beta binding protein 2
    • CKII beta-associating protein
    • CR6 interacting factor 1
    • CR6-interacting factor 1
    • CRIF1
    • G45IP_HUMAN
    • Gadd45gip1
    • Growth arrest and DNA damage inducible GADD45G interacting protein
    • growth arrest and DNA damage inducible, gamma interacting protein 1
    • Growth arrest and DNA damage-inducible proteins-interacting protein 1
    • MGC4667
    • MGC4758
    • MRP L59
    • p53 responsive gene 6
    • p53 responsive gene 6 protein
    • p53-responsive gene 6 protein
    • Papillomavirus L2 interacting nuclear protein 1
    • Papillomavirus L2-interacting nuclear protein 1
    • PLINP
    • PLINP 1
    • PLINP-1
    • PLINP1
    • PRG6
    see all
  • 機能Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
  • 組織特異性Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human GADD45GIP1 protein 画像

  • ab113863 at 3 µg analysed by 15% SDS-PAGE.

Recombinant Human GADD45GIP1 protein (ab113863) 使用論文

ab113863 has not yet been referenced specifically in any publications.

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