Recombinant Human GABA A Receptor beta 3 protein (ab114354)

製品の概要

  • 製品名
    Recombinant Human GABA A Receptor beta 3 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMV SEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLN DKKSFVHGVT
    • 分子量
      38 kDa including tags
    • 領域
      26 to 135

特性

Our Abpromise guarantee covers the use of ab114354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

    ELISA

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • ECA5
    • GABA alpha receptor beta-2 subunit
    • GABA(A) receptor subunit beta-3
    • GABAA receptor beta 3 subunit
    • GABAA receptor subunit beta 3
    • GABR B3
    • Gabrb3
    • Gamma aminobutyric acid (GABA) A receptor beta 3
    • Gamma aminobutyric acid receptor subunit beta 3
    • Gamma-aminobutyric acid receptor subunit beta-3
    • GBRB3_HUMAN
    • MGC9051
    see all
  • 機能
    Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
  • 関連疾患
    Epilepsy, childhood absence 5
  • 配列類似性
    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB3 sub-subfamily.
  • 細胞内局在
    Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

画像

  • ab114354 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

参考文献

ab114354 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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