製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q99958
    • 生物種Human
    • 配列AASWYLNHSGDLNHLPGHTFAAQQQTFPNVREMFNSHRLGIENSTLGESQ VSGNASCQLPYRSTPPLYRHAAPYSYDCTKY
    • 分子量35 kDa including tags
    • 領域421 to 501

特性

Our Abpromise guarantee covers the use of ab114305 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

    SDS-PAGE

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Drosphilia Forkhead Homolog Like 14
    • FKHL 14
    • FKHL14
    • Forkhead Box C2
    • Forkhead box protein C2
    • Forkhead related protein FKHL14
    • Forkhead-related protein FKHL14
    • FOX C2
    • Foxc2
    • FOXC2_HUMAN
    • LD
    • Mesenchyme fork head protein 1
    • Mesenchyme Forkhead 1
    • MFH 1
    • MFH 1 protein
    • MFH-1 protein
    • MFH1
    • Transcription factor FKH 14
    • Transcription factor FKH-14
    see all
  • 機能Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
  • 関連疾患Defects in FOXC2 are the cause of lymphedema hereditary type 2 (LMPH2) [MIM:153200]; also known as Meige lymphedema. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections, and physical impairment.
    Defects in FOXC2 are a cause of lymphedema-yellow nails (LYYN) [MIM:153300]. LYYN is characterized by yellow, dystrophic, thick and slowly growing nails, associated with lymphedema and respiratory involvement. Lymphedema occurs more often in the lower limbs. It can appear at birth or later in life. Onset generally follows the onset of ungual abnormalities.
    Defects in FOXC2 are a cause of lymphedema-distichiasis (LYD) [MIM:153400]. LYD is characterized by primary limb lymphedema usually starting at puberty (but in some cases later or at birth) and associated with distichiasis (double rows of eyelashes, with extra eyelashes growing from the Meibomian gland orifices).
  • 配列類似性Contains 1 fork-head DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human FOXC2 protein 画像

  • 12.5% SDS-PAGE image showing ab114305 Stained with Coomassie Blue.

Recombinant Human FOXC2 protein (ab114305) 使用論文

ab114305 has not yet been referenced specifically in any publications.

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