Recombinant human Follistatin protein (ab50163)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCN
    • 分子量
      32 kDa
    • 領域
      30 to 317

特性

Our Abpromise guarantee covers the use of ab50163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Determined by its ability to neutralize Activin A inhibitory effect of murine MPC-11 cells. The expected ED50 is 0.1-0.4 µg/ml in the presence of 7.5 ng/ml Activin A.

  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 精製度
    > 95 % SDS-PAGE.
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Activin binding protein
    • Activin-binding protein
    • Follistatin
    • FS
    • fst
    • FST_HUMAN
    • Human follistatin gene
    see all
  • 機能
    Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
  • 組織特異性
    Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.
  • 配列類似性
    Contains 3 follistatin-like domains.
    Contains 3 Kazal-like domains.
    Contains 1 TB (TGF-beta binding) domain.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab50163 has not yet been referenced specifically in any publications.

レビューと Q&A

We have two products which may be suitable for your customer as the concentration of these two can be influenced on how much water is added to the lyophilised protein:

ab50163 Follistatin protein

http://www.abcam.com/index.html?datash...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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