製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O75344
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MGGSALNQGV LEGDDAPGQS LYERLSQRML DISGDRGVLK DVIREGAGDL VAPDASVLVK YSGYLEHMDR PFDSNYFRKT PRLMKLGEDI TLWGMELGLL SMRRGELARF LFKPNYAYGT LGCPPLIPPN TTVLFEIELL DFLDCAESDK FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL LRRRSAPPEE QHLVEAAKLP VLLNLSFTYL KLDRPTIALC YGEQALIIDQ KNAKALFRCG QACLLLTEYQ KARDFLVRAQ KEQPFNHDIN NELKKLASCY RDYVDKEKEM WHRMFAPCGD GSTAGES.
    • 分子量39 kDa including tags
    • 領域1 to 327
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab123536 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Specific activity is > 50 nmoles/min/ug, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 1C in Tris-Hcl pH8.0 using chymotrypsin.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab123536 was purified by standard chromatography and filter sterilized.
  • 製品の状態Liquid
  • 備考Please prevent freeze thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 0.03% EDTA, 40% Glycerol, 0.29% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • 36 kDa FK506 binding protein
    • 36 kDa FK506-binding protein
    • 36 kDa FKBP
    • EC 5.2.1.8
    • FK506 binding protein 6
    • FK506-binding protein 6
    • FKBP 36
    • FKBP-36
    • FKBP-6
    • FKBP36
    • fkbp6
    • FKBP6_HUMAN
    • Immunophilin FKBP36
    • Peptidyl prolyl cis trans isomerase
    • Peptidyl-prolyl cis-trans isomerase FKBP6
    • PPIase
    • PPIase FKBP6
    • Rotamase
    see all
  • 機能PPIases accelerate the folding of proteins.
  • 組織特異性Detected in all tissues examined, with higher expression in testis, heart, skeletal muscle, liver, and kidney.
  • 関連疾患Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • 配列類似性Contains 1 PPIase FKBP-type domain.
    Contains 3 TPR repeats.
  • Information by UniProt

Recombinant human FKBP6 protein (ab123536) 使用論文

ab123536 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"