Recombinant Human FKBP12 protein (ab61244)

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製品の概要

法規制情報

カルタヘナ法

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種
      Human

特性

Our Abpromise guarantee covers the use of ab61244 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.

  • 製品の状態
    Liquid
  • 備考


    This protein can be used for testing rapamycin inhibition of mTOR.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

関連情報

  • 別名
    • 12 kDa FK506-binding protein
    • 12 kDa FKBP
    • Calstabin 1
    • FK506 binding protein 1
    • FK506 binding protein 12
    • FK506 binding protein 1A
    • FK506 binding protein 1A (12kD)
    • FK506 binding protein 1A 12kDa
    • FK506 binding protein T cell 12 kD
    • FK506 binding protein, T cell, 12 kD
    • FK506 binding protein12
    • FK506-binding protein 1A
    • FKB1A_HUMAN
    • FKBP 12
    • FKBP 1A
    • FKBP-12
    • FKBP-1A
    • FKBP1
    • FKBP12
    • FKBP12 Exip3
    • FKBP12C
    • fkbp1a
    • Immunophilin FKBP12
    • Peptidyl prolyl cis trans isomerase
    • Peptidyl-prolyl cis-trans isomerase FKBP1A
    • PKC12
    • PKCI2
    • PPIase
    • PPIase FKBP1A
    • Protein kinase C inhibitor 2
    • Rotamase
    see all
  • 機能
    May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • 配列類似性
    Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
    Contains 1 PPIase FKBP-type domain.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • SDS-PAGE - FKBP12 protein (His tag) (ab61244)
    SDS-PAGE - FKBP12 protein (His tag) (ab61244)

参考文献

ab61244 has not yet been referenced specifically in any publications.

ab61244 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

レビューと Q&A

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1 Review or Q&A

10
Votes: Highest First


I'm interested in some of yours product:
- cMET cytosolic domain_recombinant protein # ab60334
- FKBP12 recombinant protein # ab61244.
I can't check on datasheets any info about aminoacidic sequence.



Human FKBP12 (ab61244) is provided as full length protein with N-terminal His tag, MW= 13.1 kDa, expressed in E.coli expression system.

Active Met (c-Met) protein fragment (ab60334) is a recombinant rat MET (958-end) expressed by ba...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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