Recombinant Human FKBP12 protein (ab56524)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab56524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C. Do Not Freeze.

    Preservative: 1mM Sodium Azide
    Constituents: 50mM Sodium chloride, 10mM HEPES, 0.5mM DTT, pH 8

    Note: This product can be dissolved further into aqueous buffers for use, but these solutions should not be frozen.

関連情報

  • 別名
    • 12 kDa FK506-binding protein
    • 12 kDa FKBP
    • Calstabin 1
    • FK506 binding protein 1
    • FK506 binding protein 12
    • FK506 binding protein 1A
    • FK506 binding protein 1A (12kD)
    • FK506 binding protein 1A 12kDa
    • FK506 binding protein T cell 12 kD
    • FK506 binding protein, T cell, 12 kD
    • FK506 binding protein12
    • FK506-binding protein 1A
    • FKB1A_HUMAN
    • FKBP 12
    • FKBP 1A
    • FKBP-12
    • FKBP-1A
    • FKBP1
    • FKBP12
    • FKBP12 Exip3
    • FKBP12C
    • fkbp1a
    • Immunophilin FKBP12
    • Peptidyl prolyl cis trans isomerase
    • Peptidyl-prolyl cis-trans isomerase FKBP1A
    • PKC12
    • PKCI2
    • PPIase
    • PPIase FKBP1A
    • Protein kinase C inhibitor 2
    • Rotamase
    see all
  • 機能May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • 配列類似性Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
    Contains 1 PPIase FKBP-type domain.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human FKBP12 protein 画像

  • Anti-FKBP12 antibody (ab24373) at 1 µg/ml + Recombinant Human FKBP12 protein (ab56524) at 0.1 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 2 minutes

Recombinant Human FKBP12 protein (ab56524) 使用論文

ab56524 has not yet been referenced specifically in any publications.

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Thank you for your reply.

I would be happy to send you ab31353 as a replacement antibody. To do this, would you also be able to provide me with either the Abcam order number, or the PO# number that was used to make the original purchase.
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Thank you for your enquiry. Some of the previous lots of this product have also been tested using the Bradford assay. It is not done for every lot but the results between Bradofrd and standard UV absorbance do seem to correlate for the lots tested....

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Thank you for your enquiry. I can confirm that the concentration for ab56524 is 1.200 mg/ml. Regarding measurements, the protein concentration is determined by UV absorbance and the internal standard used we use is a protein standard (albumin from ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"