Recombinant Human Fibronectin Fragment III.1 protein (ab58865)

製品の概要

  • 製品名Recombinant Human Fibronectin Fragment III.1 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab58865 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C.

    Preservative: None

  • 再構成Reconstitute with 0.5 ml of sterile PBS per 0.5 mg vial. The stock solution can be further diluted with sterile PBS or cell culture medium.

関連情報

  • 別名
    • CIG
    • Cold insoluble globulin
    • Fibronectin 1
    • Fibronectin precursor
    • FINC
    • FN
    • LETS
    • Migration stimulating factor
    • MSF
    see all
  • 関連性Fibronectins are made of two subunits linked by disulfide bonds at the C terminal. In the extracellular matrix fibrils, fibronectins are further disulfide bonded into high molecular weight polymers. Fibronectin subunits vary in size between approximately 235 and 270 kDa depending on tissue and species. Each subunit is made of repeating modules of three types: I, II, and III. There are 12 type I repeats, approximately 45 amino acids long, clustered in three groups, two adjacent type II repeats each 60 amino acids long, and 15-17 type III repeats each about 90 amino acids long. Type I and type II each contains two disulfide bonds, while type III lacks disulfide bonds. There are two free sulfhydryl groups per subunit at the type III repeat. Recombinant fragment III1-C, modeled after the C-terminal two-thirds of the III1 repeat, was found to bind to fibronectin and induce spontaneous disulfide crosslinking of the fibronectin molecules into multimers, which resemble matrix fibrils.(Moria, A., et al., Nature, 367, 193 (1994).
  • 細胞内局在Secreted protein; extracellular space; extracellular matrix

Recombinant Human Fibronectin Fragment III.1 protein (ab58865) 使用論文

ab58865 has not yet been referenced specifically in any publications.

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