The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
< 0.100 Eu/µg
% SDS-PAGE. Greater than 95% by SDS-PAGE.
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.6 Constituents: 0.44% Sodium chloride, 0.064% Tris
Centrifuge the vial prior to opening. Reconstitute in 5-10 mM Sodium Phosphate, pH 8.0 to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use. Repeated freeze thaw cycles will result in some loss of activity.
Fibroblast growth factor 15
Fibroblast growth factor 19
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
Expressed in fetal brain, cartilage, retina, and adult gall bladder.
Belongs to the heparin-binding growth factors family.