製品の概要

  • 製品名Recombinant Human Fascin protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q16658
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MTANGTAEAV QIQFGLINCG NKYLTAEAFG FKVNASASSL KKKQIWTLEQ PPDEAGSAAV CLRSHLGRYL AADKDGNVTC EREVPGPDCR FLIVAHDDGR WSLQSEAHRR YFGGTEDRLS CFAQTVSPAE KWSVHIAMHP QVNIYSVTRK RYAHLSARPA DEIAVDRDVP WGVDSLITLA FQDQRYSVQT ADHRFLRHDG RLVARPEPAT GYTLEFRSGK VAFRDCEGRY LAPSGPSGTL KAGKATKVGK DELFALEQSC AQVVLQAANE RNVSTRQGMD LSANQDEETD QETFQLEIDR DTKKCAFRTH TGKYWTLTAT GGVQSTASSK NASCYFDIEW RDRRITLRAS NGKFVTSKKN GQLAASVETA GDSELFLMKL INRPIIVFRG EHGFIGCRKV TGTLDANRSS YDVFQLEFND GAYNIKDSTG KYWTVGSDSA VTSSGDTPVD FFFEFCDYNK VAIKVGGRYL KGDHAGVLKA SAETVDPASL WEY
    • 分子量57 kDa including tags
    • 領域1 to 493
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab99240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab99240 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8.0

関連情報

  • 別名
    • 55 kDa actin bundling protein
    • 55 kDa actin-bundling protein
    • Actin bundling protein
    • actin bundling protein, 55-KD
    • FAN 1
    • FAN1
    • Fascin
    • Fascin 1
    • Fascin actin bundling protein 1
    • Fascin homolog 1
    • Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus)
    • Fascin, sea urchin, homolog of, 1
    • Fascin1
    • FLJ38511
    • FSCN 1
    • FSCN1
    • FSCN1_HUMAN
    • HSN
    • p55
    • Singed (Drosophila) like (sea urchin fascin homolog like)
    • Singed drosophila homolog like
    • Singed like (fascin homolog sea urchin)
    • Singed like (fascin homolog sea urchin) (Drosophila)
    • Singed like protein
    • Singed, drosophila, homolog of
    • Singed-like protein
    • SNL
    • Strongylocentrotus purpuratus
    see all
  • 機能Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
  • 組織特異性Ubiquitous.
  • 配列類似性Belongs to the fascin family.
  • ドメインComposed of four beta-trefoil domains.
  • 翻訳後修飾Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.
  • 細胞内局在Cytoplasm > cytoskeleton. Cell projection > filopodium. Cell projection > invadopodium.
  • Information by UniProt

Recombinant Human Fascin protein 画像

  • 15% SDS-PAGE showing ab99240 at approximately 56.7kDa (3µg).

Recombinant Human Fascin protein (ab99240) 使用論文

ab99240 has not yet been referenced specifically in any publications.

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