製品の概要

  • 製品名Recombinant Human FANCG protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号O15287
    • 生物種Human
    • 配列MSRQTTSVGSSCLDLWREKNDRLVRQAKVAQNSGLTLRRQQLAQDALE GLRGLLHSLQGLPAAVPVLPLELTVTCNFIILRASLAQGFTEDQAQDIQR SLERVLETQEQQGPRLEQGLRELWDSVLRASCLLPELLSALHRLVGLQAA LWLSADRLGDLALLLETLNGSQSGASKDLLLLLKTWSPPAEELDAPLTLQ DAQGLKDVLLTAFAYRQGLQELITGNPDKALSSLHEAASGLCPRPVLVQV YTALGSCHRKMGNPQRALLYLVAALKEGSAWGPPLLEASRLYQQLGDTTA ELESLELLVEALNVPCSSKAPQFLIEVELLLPPPDLASPLHCGTQSQTKH ILASRCLQTGRAGDAAEHYLDLLALLLDSSEPRFSPPPSPPGPCMPEVFL EAAVALIQAGRAQDALTLCEELLSRTSSLLPKMSRLWEDARKGTKELPYC PLWVSATHLLQGQAWVQLGAQKVAISEFSRCLELLFRATPEEKEQGAAFN CEQGCKSDAALQQLRAAALISRGLEWVASGQDTKALQDFLLSVQMCPGNR DTYFHLLQTLKRLDRRDEATALWWRLEAQTKGSHEDALWSLPLYLESYLS WIRPSDRDAFLEEFRTSLPKSCDL
    • 分子量95 kDa including tags
    • 領域1 to 622

特性

Our Abpromise guarantee covers the use of ab114925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • DNA repair protein XRCC9
    • FAG
    • FANCG
    • FANCG_HUMAN
    • Fanconi anaemia complementation group G
    • Fanconi anemia group G protein
    • Protein FACG
    • X ray repair, complementing defective, in Chinese hamster cells 9
    • X-ray repair, complementing defective, in Chinese hamster, 9
    • XRCC9
    see all
  • 機能DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
  • 組織特異性Highly expressed in testis and thymus. Found in lymphoblasts.
  • 関連疾患Defects in FANCG are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
  • 配列類似性Contains 4 TPR repeats.
  • 細胞内局在Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
  • Information by UniProt

Recombinant Human FANCG protein 画像

  • 12.5% SDS-PAGE showing ab114925 at approximately 94.53kDa.
    Stained with Coomassie Blue.

Recombinant Human FANCG protein (ab114925) 使用論文

ab114925 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"