製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MVAQVSITKC SSDMNGYCLH GQCIYLVDMS QNYCRCEVGY TGVRCEHFFL
    • 分子量
      6 kDa
    • 領域
      60 to 108

関連製品

特性

Our Abpromise guarantee covers the use of ab116471 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is < 2.0 ng/ml, corresponding to a specific activity of > 500,000 units/mg.
  • アプリケーション

    SDS-PAGE

    HPLC

    Functional Studies

  • 精製度
    > 97 % SDS-PAGE.
    ab116471 is purified by proprietary chromatographic techniques. Purity is greater than 97.0% as determined by RP-HPLC and SDS-PAGE.
  • 製品の状態
    Lyophilised
  • 備考
    ab116471, although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ab116471 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Please see notes section.

    pH: 7.40
    Constituents: PBS, 0.76% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    It is recommended to reconstitute in sterile Ultra pure water at not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

関連情報

  • 別名
    • Epiregulin
    • EPR
    • ER
    • Ereg
    • EREG_HUMAN
    • Proepiregulin
    see all
  • 機能
    May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.
  • 組織特異性
    In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon.
  • 配列類似性
    Contains 1 EGF-like domain.
  • 細胞内局在
    Cell membrane and Secreted > extracellular space.
  • Information by UniProt

参考文献

ab116471 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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