Recombinant Human Ephrin B2 protein (ab92862)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来HEK 293 cells
  • アミノ酸配列
    • 生物種Human
    • 領域1 to 227

特性

Our Abpromise guarantee covers the use of ab92862 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

    SDS-PAGE

  • 製品の状態Lyophilised
  • 備考After reconstitution, store in working aliquots at -80ºC.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS, pH 7.4

  • 再構成Please add 20ul of PBS to make 0.5mg/ml

関連情報

  • 別名
    • EFN B2
    • EFNB 2
    • Efnb2
    • EFNB2_HUMAN
    • Eph related receptor tyrosine kinase ligand 5
    • EPH-related receptor tyrosine kinase ligand 5
    • ephrin B2
    • Ephrin-B2
    • EphrinB2
    • EPLG 5
    • EPLG5
    • Htk L
    • HTK ligand
    • HTK-L
    • HTKL
    • LERK 5
    • LERK-5
    • LERK5
    • Ligand of eph related kinase 5
    • MGC126226
    • MGC126227
    • MGC126228
    • OTTMUSP00000024973
    see all
  • 機能Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
    (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.
  • 組織特異性Lung and kidney.
  • 配列類似性Belongs to the ephrin family.
    Contains 1 ephrin RBD (ephrin receptor-binding) domain.
  • 翻訳後修飾Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Human Ephrin B2 protein 画像

  • 10% SDS-PAGE of ab92862 stained with Coomassie Blue (CB) and immunoblotted with polyclonal antibody against Human Ephrin B2 (WB)

Recombinant Human Ephrin B2 protein (ab92862) 使用論文

ab92862 has not yet been referenced specifically in any publications.

Product Wall

Purity: ³95% (SDS-PAGE)

Expressed in HEK293 cells

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Thank you for your enquiry.

Yes, it is the fusion protein (472 aa with tag, MWt 52.9kDa) that is at 1mg/ml concentration. The mass of the fusion protein includes the 6x His tag.

I hope this is helpful. Please contact me again if you...

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Vielen Dank für Ihre Geduld! Endlich (!) hat das Labor, welches ab92862 herstellt, sich mit der Information zur Konstruktion des Ephrin B2-Fc-Chimärproteins gemeldet. Es besteht vom N- zum C-Terminus aus: EphrinB2 -IgG1Fc -Histag (Details siehe An...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"