Recombinant Human Ephrin B2 protein (ab113609)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P52799
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMGSHMIVLEPIYWNSSNSKFLPGQGLVLYP QIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCA KPDQDIKFTIKFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGV CQTRAMKILMKVGQDASSAGSTRNKDPTRRPELEAGTNGRSSTTSPFVKP NPGSSTDGNSAGHSGNNILGSEVALFA
    • 分子量25 kDa including tags
    • 領域28 to 229
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Mass Spectrometry

    SDS-PAGE

  • 質量分析
    MALDI-TOF
  • 精製度> 85 % SDS-PAGE.
    ab113609 was purified to > 85% by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 20% Glycerol, 1.17% Sodium chloride

関連情報

  • 別名
    • EFN B2
    • EFNB 2
    • Efnb2
    • EFNB2_HUMAN
    • Eph related receptor tyrosine kinase ligand 5
    • EPH-related receptor tyrosine kinase ligand 5
    • ephrin B2
    • Ephrin-B2
    • EphrinB2
    • EPLG 5
    • EPLG5
    • Htk L
    • HTK ligand
    • HTK-L
    • HTKL
    • LERK 5
    • LERK-5
    • LERK5
    • Ligand of eph related kinase 5
    • MGC126226
    • MGC126227
    • MGC126228
    • OTTMUSP00000024973
    see all
  • 機能Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
    (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.
  • 組織特異性Lung and kidney.
  • 配列類似性Belongs to the ephrin family.
    Contains 1 ephrin RBD (ephrin receptor-binding) domain.
  • 翻訳後修飾Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant Human Ephrin B2 protein 画像

  • 15% SDS-PAGE analysis of ab113609 (3µg)

Recombinant Human Ephrin B2 protein (ab113609) 使用論文

ab113609 has not yet been referenced specifically in any publications.

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