Recombinant human Eph receptor A4 protein (ab84575)

製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • 生物種
      Human
    • 領域
      610 to 887

特性

Our Abpromise guarantee covers the use of ab84575 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    Specific activity of Eph receptor A4 was determined to be 83 nmol/min/mg as per activity assay protocol.
  • アプリケーション

    Western blot

    Functional Studies

    SDS-PAGE

  • 精製度
    > 90 % SDS-PAGE.
    Purity was determined to be >90% by densitometry.
  • 製品の状態
    Liquid
  • 備考

    ab204877 (Poly (4:1 Glu, Tyr) peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • Cek 8
    • CEK8
    • EK8
    • eph receptor a4
    • EPH-like kinase 8
    • EPHA4
    • EPHA4_HUMAN
    • Ephrin type-A receptor 4
    • HEK 8
    • hEK8
    • Receptor protein-tyrosine kinase HEK8
    • SEK
    • Sek 1
    • TYRO 1 protein tyrosine kinase
    • TYRO1
    • Tyrosine-protein kinase receptor SEK
    • Tyrosine-protein kinase TYRO1
    see all
  • 機能
    Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A4 and -A5. Binds more poorly to ephrin-A2 and -A3. May play a role in a signal transduction process involved in hindbrain pattern formation.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 protein kinase domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • ドメイン
    The protein kinase domain mediates interaction with NGEF/ephexin-1.
  • 細胞内局在
    Membrane.
  • Information by UniProt

画像

  • Specific activity of Eph receptor A4 was determined to be 83 nmol/min/mg as per activity assay protocol.
  • Purity of Eph receptor A4 was determined to be >90% by densitometry. approx, MW 58kDa.

参考文献

ab84575 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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