Recombinant Human Endothelin A Receptor protein (ab114239)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P25101
    • 生物種Human
    • 配列VISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHN YCPQQTKITSAFK
    • 分子量33 kDa including tags
    • 領域18 to 80

特性

Our Abpromise guarantee covers the use of ab114239 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Ednra
    • EDNRA_HUMAN
    • Endothelin 1 receptor precursor
    • Endothelin 1 specific receptor
    • Endothelin A receptor
    • Endothelin ET A receptor
    • Endothelin receptor ET1 specific type
    • Endothelin receptor subtype A
    • Endothelin receptor type A
    • Endothelin-1 receptor
    • ET A
    • ET-A
    • ETA
    • ETA R
    • ETA-R
    • ETAR
    • ETRA
    • hET AR
    • hET-AR
    see all
  • 機能Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
  • 組織特異性Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily.
  • 細胞内局在Cell membrane.
  • Information by UniProt

Recombinant Human Endothelin A Receptor protein 画像

  • 12.5% SDS-PAGE showing ab114239 at approximately 32.56kDa stained with Coomassie Blue.

Recombinant Human Endothelin A Receptor protein (ab114239) 使用論文

ab114239 has not yet been referenced specifically in any publications.

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Thank you for your reply.


Both recombinant fragment peptide are validated for ELISA, but the protocol used will depend largely on the antibodies being used in the assay. The data I sent previously included relevant protocol information....

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Thank you for your reply.

I have forwarded all available ELISA data for ab114239.



Please do not hesitate to contact me if you have any additional questions.

Thank you for your reply.


Both proteins have been used in different ELISA assays:


Regarding ab114239, this was tested in a sELISA. On the other hand, ab114259 was tested in a simple ELISA assay in which the protein was c...

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Thank you for contacting Abcam regarding the proteins ab114239 and ab114259.


I have reviewed the product specifications of these proteins as well as the kit protocols the customer is using. It is important to note that both of these pro...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"