Recombinant Human EIF3S1 protein (ab113578)

製品の概要

  • 製品名
    Recombinant Human EIF3S1 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMKISEKKKIAEKIKEKERQQKKRQEEIKKR LEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAM NPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKK ITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDG GYVQDYEDFM
    • 分子量
      24 kDa including tags
    • 領域
      70 to 258
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab113578 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% Tris HCl, 0.03% DTT, 10% Glycerol, 1.17% Sodium chloride

関連情報

  • 別名
    • eIF 3 alpha
    • eIF-3-alpha
    • eIF3 alpha
    • eIF3 p35
    • eIF3j
    • EIF3J_HUMAN
    • EIF3S 1
    • EIF3S1
    • Eukaryotic translation initiation factor 3 subunit 1
    • Eukaryotic translation initiation factor 3 subunit J
    • Eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD)
    • Eukaryotic translation initiation factor 3, subunit 1 alpha, 35kD
    see all
  • 機能
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
  • 配列類似性
    Belongs to the eIF-3 subunit J family.
  • 翻訳後修飾
    Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt

画像

  • 15% SDS-PAGE showing ab113578 at approximately 24.0kDa (3µg).

参考文献

ab113578 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab113578.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録