Recombinant Human EIF3S1 protein (ab113578)

製品の概要

  • 製品名Recombinant Human EIF3S1 protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号O75822
    • 生物種Human
    • 配列MGSSHHHHHHSSGLVPRGSHMKISEKKKIAEKIKEKERQQKKRQEEIKKR LEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAM NPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKK ITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDG GYVQDYEDFM
    • 分子量24 kDa including tags
    • 領域70 to 258
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab113578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度> 90 % SDS-PAGE.
    ab113578 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% Tris HCl, 0.03% DTT, 10% Glycerol, 1.17% Sodium chloride

関連情報

  • 別名
    • eIF 3 alpha
    • eIF-3-alpha
    • eIF3 alpha
    • eIF3 p35
    • eIF3j
    • EIF3J_HUMAN
    • EIF3S 1
    • EIF3S1
    • Eukaryotic translation initiation factor 3 subunit 1
    • Eukaryotic translation initiation factor 3 subunit J
    • Eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD)
    • Eukaryotic translation initiation factor 3, subunit 1 alpha, 35kD
    see all
  • 機能Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.
  • 配列類似性Belongs to the eIF-3 subunit J family.
  • 翻訳後修飾Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
  • 細胞内局在Cytoplasm.
  • Information by UniProt

Recombinant Human EIF3S1 protein 画像

  • 15% SDS-PAGE showing ab113578 at approximately 24.0kDa (3µg).

Recombinant Human EIF3S1 protein (ab113578) 使用論文

ab113578 has not yet been referenced specifically in any publications.

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