製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      VRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFKVPIQANETLVG AVINNVSEAMETLTRITEELVPVPGS
    • 分子量
      34 kDa including tags
    • 領域
      162 to 237

特性

Our Abpromise guarantee covers the use of ab114209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • EA6
    • EAA1_HUMAN
    • EAAT1
    • Excitatory amino acid transporter 1
    • FLJ25094
    • GLAST
    • GLAST-1
    • GLAST1
    • Glial high affinity glutamate transporter
    • glutamate/aspartate transporter, high affinity, sodium-dependent
    • High affinity neuronal glutamate transporter
    • Slc1a3
    • Sodium dependent glutamate/aspartate transporter
    • Sodium-dependent glutamate/aspartate transporter 1
    • Solute carrier family 1 (glial high affinity glutamate transporter) member 3
    • Solute carrier family 1 member 3
    see all
  • 機能
    Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
  • 組織特異性
    Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.
  • 関連疾患
    Defects in SLC1A3 are the cause of episodic ataxia type 6 (EA6) [MIM:612656]. EA6 is characterized by episodic ataxia, seizures, migraine and alternating hemiplegia.
  • 配列類似性
    Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A3 subfamily.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Membrane.
  • Information by UniProt

Recombinant Human EAAT1 protein 画像

  • 12.5% SDS-PAGE analysis of ab114209 stained with Coomassie Blue.

Recombinant Human EAAT1 protein (ab114209) 使用論文

ab114209 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114209.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録