Recombinant Human E2F8 protein (ab153513)
Key features and details
- Expression system: Wheat germ
- Tags: GST tag N-Terminus
- Suitable for: WB, ELISA
製品の詳細
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製品名
Recombinant Human E2F8 protein -
発現系
Wheat germ -
タンパク質長
Full length protein -
Animal free
No -
由来
Recombinant -
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生物種
Human -
配列
MAQLAAICKMQLEEQSSESRQKVKVQLARSGPCKPVAPLDPPVNAEMELT APSLIQPLGMVPLIPSPLSSAVPLILPQAPSGPSYAIYLQPTQAHQSVTP PQGLSPTVCTTHSSKATGSKDSTDATTEKAANDTSKASASTRPGSLLPAP ERQGAKSRTREPAGERGSKRASMLEDSGSKKKFKEDLKGLENVSATLFPS GYLIPLTQCSSLGAESILSGKENSSALSPNHRIYSSPIAGVIPVTSSELT AVNFPSFHVTPLKLMVSPTSVAAVPVGNSPALASSHPVPIQNPSSAIVNF TLQHLGLISPNVQLSASPGSGIVPVSPRIESVNVAPENAGTQQGRATNYD SPVPGQSQPNGQSVAVTGAQQPVPVTPKGSQLVAESFFRTPGGPTKPTSS SCMDFEGANKTSLGTLFVPQRKLEVSTEDVH -
領域
1 to 431 -
タグ
GST tag N-Terminus
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特性
Our Abpromise guarantee covers the use of ab153513 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Western blot
ELISA
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製品の状態
Liquid -
備考
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00
Constituents: 0.31% Glutathione, 0.79% Tris HCl
関連情報
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別名
- E2F 8
- E2F family member 82
- E2F transcription factor 8
see all -
機能
Along with E2F7, inhibitor of E2F-dependent transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Directly represses E2F1 transcription. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. -
配列類似性
Belongs to the E2F/DP family. -
ドメイン
Both DNA-binding domains are required for DNA-binding and are proposed to form an intramolecular structure that is similar to the winged helix structure of the E2F-DP heterodimer. -
細胞内局在
Nucleus. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab153513 は論文での使用が確認できていません。