製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMASTVGAAGWKGELPKAGGSPAPGPETPAI SPSKRARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPP MEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVG VVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGS TGKN
    • 分子量
      22 kDa including tags
    • 領域
      70 to 252
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab99388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab99388 is purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • Deoxyuridine 5' triphosphate nucleotidohydrolase, nuclear isoform
    • Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
    • Deoxyuridine triphosphatase
    • dut
    • DUT_HUMAN
    • dUTP nucleotidohydrolase
    • dUTP pyrophosphatase
    • dUTPase
    • FLJ20622
    see all
  • 機能
    This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
  • 組織特異性
    Found in a variety of tissues.
  • パスウェイ
    Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.
  • 配列類似性
    Belongs to the dUTPase family.
  • 翻訳後修飾
    Phosphorylation in mature T-cells occur in a cell cycle-dependent manner.
  • 細胞内局在
    Mitochondrion and Nucleus.
  • Information by UniProt

Recombinant Human DUT protein 画像

  • 15% SDS-PAGE analysis of 3µg ab99388.

Recombinant Human DUT protein (ab99388) 使用論文

ab99388 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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