製品の概要

  • 製品名
    Recombinant Human Dub3 protein
  • タンパク質長
    Protein fragment

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      ESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHP EQQSSLLNLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ
    • 分子量
      37 kDa including tags
    • 領域
      431 to 530

特性

Our Abpromise guarantee covers the use of ab112436 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

    ELISA

  • 製品の状態
    Liquid
  • 備考
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • Cytokine inducible Deubiquitinating Enzyme
    • Deubiquitinating enzyme 17-like protein 2
    • Deubiquitinating enzyme 3
    • Deubiquitinating protein 3
    • DUB-3
    • DUB3 protein
    • U17L2_HUMAN
    • Ubiquitin carboxyl-terminal hydrolase 17-like protein 2
    • Ubiquitin thiolesterase 17-like protein 2
    • Ubiquitin-specific-processing protease 17-like protein 2
    • USP17L2
    see all
  • 機能
    Deubiquitinating enzyme that specifically removes conjugated ubiquitin from CDC25A, thereby playing a key role in cell cycle regulation. Deubiquitination of CDC25A prevents its degradation by the proteasome during the G1/S and G2/M phases of the cell cycle and is required for cell-cycle progression. Has transforming capabilities on cell lines. May also function in cell apoptosis.
  • 組織特異性
    Broadly expressed.
  • 配列類似性
    Belongs to the peptidase C19 family. USP17 subfamily.
  • 細胞内局在
    Nucleus.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE showing ab112436 at approximately 36.63kDa stained with Coomassie Blue.

参考文献

ab112436 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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