製品の概要

  • 製品名
    Recombinant Human DTYMK protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHH SSGLVPRGSH MAARRGALIV LEGVDRAGKS TQSRKLVEAL CAAGHRAELL RFPERSTEIG KLLSSYLQKK SDVEDHSVHL LFSANRWEQV PLIKEKLSQG VTLVVDRYAF SGVAFTGAKE NFSLDWCKQP DVGLPKPDLV LFLQLQLADA AKRGAFGHER YENGAFQERA LRCFHQLMKD TTLNWKMVDA SKSIEAVHED IRVLSEDAIR TATEKPLGEL WK
    • 分子量
      24 kDa
    • 領域
      1 to 212
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab109838 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 95 % SDS-PAGE.
    No detergents such as urea, Triton or Tween have been used to purify the protein. Purified by using anion exchange chromatography (DEAE sepharose resin) and gel filtration chromatography (Sephacryl S 200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 製品の状態
    Liquid
  • 備考


    Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.04% DTT, 0.58% Sodium chloride

関連情報

  • 別名
    • CDC8
    • deoxythymidylate kinase
    • Deoxythymidylate kinase (thymidylate kinase)
    • dTMP kinase
    • Dtymk
    • FLJ44192
    • KTHY_HUMAN
    • MGC198617
    • OTTHUMP00000164604
    • OTTHUMP00000200145
    • OTTHUMP00000200146
    • PP3731
    • Thymidylate kinase
    • TMPK
    • TYMK
    see all
  • 機能
    Catalyzes the conversion of dTMP to dTDP.
  • パスウェイ
    Pyrimidine metabolism; dTTP biosynthesis.
  • 配列類似性
    Belongs to the thymidylate kinase family.
  • Information by UniProt

画像

  • SDS-PAGE analysis of ab109838: (1) MW marker, (2) ab109838 at 3µg
    Gel concentration: 15%

参考文献

This product has been referenced in:
  • Su JY & Sclafani RA Molecular cloning and expression of the human deoxythymidylate kinase gene in yeast. Nucleic Acids Res 19:823-7 (1991). Read more (PubMed: 2017365) »
  • Cummins RR & Balinsky D Activities of some enzymes of pyrimidine and DNA synthesis in a rat transplantable hepatoma and human primary hepatomas, in cell lines derived from these tissues, and in human fetal liver. Cancer Res 40:1235-9 (1980). Read more (PubMed: 6244089) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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