Recombinant Human Dopamine D2 Receptor protein (ab112281)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVF GNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVG EW KFSRIHCDIF
    • 分子量
      38 kDa including tags
    • 領域
      1 to 110
    • タグ
      GST tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab112281 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    useful for Antibody Production and Protein Array
  • アプリケーション

    Western blot

    SDS-PAGE

    ELISA

    Peptide Array

  • 製品の状態
    Liquid
  • 備考
    Best use within three months from the date of receipt of this protein.useful for Antibody Production and Protein Array
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Reduced glutathione

関連情報

  • 別名
    • D(2) dopamine receptor
    • D2 dopamine receptor
    • D2DR
    • D2R
    • Dopamine D2 receptor
    • Dopamine receptor D2
    • DRD 2
    • DRD2
    • DRD2_HUMAN
    see all
  • 機能
    This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
  • 関連疾患
    Defects in DRD2 are associated with dystonia type 11 (DYT11) [MIM:159900]; also known as alcohol-responsive dystonia. DYT11 is a myoclonic dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. DYT11 is characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Inheritance is autosomal dominant. The age of onset, pattern of body involvement, presence of myoclonus and response to alcohol are all variable.
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue with recombinant protein.

参考文献

ab112281 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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