Recombinant Human DOPA Decarboxylase protein (ab40029)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab40029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

関連情報

  • 別名
    • AADC
    • Aromatic L Amino Acid Decarboxylase
    • Aromatic-L-amino-acid decarboxylase
    • DDC
    • DDC_HUMAN
    • DOPA decarboxylase
    • DOPA decarboxylase (aromatic L-amino acid decarboxylase)
    see all
  • 機能Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
  • パスウェイCatecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 2/2.
  • 関連疾患Defects in DDC are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD) [MIM:608643]. AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. It causes developmental and psychomotor delay, poor feeding, lethargy, ptosis, intermittent hypothermia, gastrointestinal disturbances. The onset is early in infancy and inheritance is autosomal recessive.
  • 配列類似性Belongs to the group II decarboxylase family.
  • Information by UniProt

Recombinant Human DOPA Decarboxylase protein 画像

Recombinant Human DOPA Decarboxylase protein (ab40029) 使用論文

ab40029 has not yet been referenced specifically in any publications.

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