Recombinant Human Dnmt3L protein (ab112413)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q9UJW3
    • 生物種Human
    • 配列LVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSSRHWA LVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL
    • 分子量37 kDa including tags
    • 領域288 to 387

特性

Our Abpromise guarantee covers the use of ab112413 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性This product is useful for Antibody Production and Protein Array
  • アプリケーション

    ELISA

    Western blot

    Peptide Array

    SDS-PAGE

  • 製品の状態Liquid
  • 備考Best used within three months from the date of receipt This product is useful for Antibody Production and Protein Array
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione
    Note: Glutathione is reduced.

関連情報

  • 別名
    • Cytosine 5 methyltransferase 3 like protein
    • DNA (cytosine 5 ) methyltransferase 3 like
    • DNA (cytosine-5)-methyltransferase 3-like
    • DNA cytosine 5 methyltransferase 3 like protein
    • DNA methyltransferase 3 like protein
    • DNM3L_HUMAN
    • Dnmt 3L
    • Dnmt3l
    • Human cytosine 5 methyltransferase 3 like protein
    • MGC1090
    see all
  • 機能Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
  • 組織特異性Expressed at low levels in several tissues including testis, ovary, and thymus.
  • 配列類似性Belongs to the C5-methyltransferase family.
    Contains 1 ADD-type zinc finger.
  • 細胞内局在Nucleus.
  • Information by UniProt

Recombinant Human Dnmt3L protein 画像

  • 12.5% SDS-PAGE image, using ab112413. (Stained with Coomassie Blue)

Recombinant Human Dnmt3L protein (ab112413) 使用論文

ab112413 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"