Recombinant Human DNAJC3 protein (ab114761)

製品の概要

  • 製品名
    Recombinant Human DNAJC3 protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAA GQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQL KMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVFPVPSLLGLQRSLLDDLY LLFWFFLMKKVTFRCLSSAISECLPQSLNLMKFNLLISFLLLWTVRLVSC LRSIHYAVGSKTFLISSKSFMVLCFIFKPIVYLS
    • 分子量
      52 kDa including tags
    • 領域
      1 to 234

関連製品

特性

Our Abpromise guarantee covers the use of ab114761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 µg/ul.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • DnaJ (Hsp40) homolog subfamily C member 3
    • DnaJ homolog subfamily C member 3
    • DNAJC3
    • DNJC3_HUMAN
    • double-stranded RNA-activated protein kinase inhibitor
    • Endoplasmic reticulum DnaJ protein 6
    • ERdj6
    • HP58
    • Interferon induced, double stranded RNA activated protein kinase inhibitor
    • Interferon-induced
    • P58
    • p58 ipk
    • P58IPK
    • PRKRI
    • Protein kinase inhibitor of 58 kDa
    • Protein kinase inhibitor p58
    • Protein kinase interferon inducible double stranded RNA dependent inhibitor
    see all
  • 機能
    Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
  • 組織特異性
    Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels.
  • 配列類似性
    Contains 1 J domain.
    Contains 9 TPR repeats.
  • ドメイン
    The J domain mediates interaction with HSPA8.
  • 細胞内局在
    Endoplasmic reticulum.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE Stained with Coomassie Blue showing ab114761 at approximately 51.85kDa.

参考文献

ab114761 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab114761.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録