Recombinant Human DNAJB11 protein (ab105636)

製品の概要

  • 製品名
    Recombinant Human DNAJB11 protein
  • タンパク質長
    Full length protein

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMGRDFYKILGVPRSASIKDIKKAYRKLALQ LHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSS HGDIFSHFFGDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFV EVVRNKPVARQAPGKRKCNCRQEMRTTQLGPGRFQMTQEVVCDECPNVKL VNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIF ERRGDDLYTNVTISLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLWK KGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKV YNGLQGY
    • 分子量
      41 kDa including tags
    • 領域
      23 to 358
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab105636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    Purified using conventional chromatography techniques.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8

関連情報

  • 別名
    • ABBP-2
    • ABBP2
    • APOBEC1 binding protein 2
    • APOBEC1-binding protein 2
    • DJ9
    • DJB11_HUMAN
    • DnaJ (Hsp40) homolog subfamily B member 11
    • DnaJ homolog subfamily B member 11
    • DnaJ protein homolog 9
    • DNAJB11
    • EDJ
    • ER associated DNAJ
    • ER associated dnaJ protein 3
    • ER associated Hsp40 co chaperone
    • ER-associated DNAJ
    • ER-associated dnaJ protein 3
    • ER-associated Hsp40 co-chaperone
    • ERdj3
    • ERJ3
    • ERj3p
    • hDj-9
    • hDj9
    • HEDJ
    • Human DnaJ protein 9
    • PWP1 interacting protein 4
    • PWP1-interacting protein 4
    see all
  • 機能
    Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.
  • 組織特異性
    Widely expressed.
  • 配列類似性
    Contains 1 J domain.
  • 翻訳後修飾
    Contains high-mannose Endo H-sensitive carbohydrates.
    Cys-169, Cys-171, Cys-193 and Cys-196 form intramolecular disulfide bonds. The preferential partner for each Cys is not known.
    Thr-188 was reported (PubMed:17525332) to be phosphorylated upon DNA damage by ATM or ATR; however as this position has been shown to be in the ER lumen, the in vivo relevance is not proven.
  • 細胞内局在
    Endoplasmic reticulum lumen. Associated with the ER membrane in a C-terminally epitope-tagged construct.
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of ab105636 (3ug)

参考文献

ab105636 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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