Recombinant Human DNA Polymerase beta protein (ab111641)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MGSSHHHHHHSSGLVPRGSHMSKRKAPQETLNGGITDMLTELANFEKNVS QAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATG KLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNED KLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSK GETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNK NMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREP KDRSE
    • 分子量
      40 kDa including tags
    • 領域
      1 to 335
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab111641 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 質量分析
    MALDI-TOF
  • 精製度
    > 90 % SDS-PAGE.
    ab111641 is purified using conventional chromatography.
  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 30% Glycerol, 0.02% DTT, 0.58% Sodium chloride, 69% Tris HCl

関連情報

  • 別名
    • DNA directed DNA polymerase beta
    • DNA pol beta
    • DNA polymerase beta
    • DNA polymerase beta subunit
    • DPOLB_HUMAN
    • MGC125976
    • Pol B
    • Pol beta
    • POLB
    • Polymerase (DNA directed) beta
    see all
  • 機能
    Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • 配列類似性
    Belongs to the DNA polymerase type-X family.
  • ドメイン
    Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.
  • 翻訳後修飾
    Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.
  • 細胞内局在
    Nucleus, Cytoplasm
  • Information by UniProt

画像

  • 15% SDS-PAGE analysis of ab111641 (3 µg)

参考文献

ab111641 has not yet been referenced specifically in any publications.

レビューと Q&A

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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