Recombinant Human DFNA5/GSDME protein (ab116824)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Wheat germ
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPK YQFLSLTLGDVLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVK LNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEG RNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGN VTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRI DSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFA ELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKP RQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSA AALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQR LFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS
    • 分子量
      81 kDa including tags
    • 領域
      1 to 496

特性

Our Abpromise guarantee covers the use of ab116824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態
    Liquid
  • 備考
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

関連情報

  • 別名
    • 2310037D07Rik
    • 4932441K13Rik
    • Deafness, autosomal dominant 5
    • Deafness, autosomal dominant 5 protein
    • DFNA5
    • DFNA5 gene
    • DFNA5_HUMAN
    • Dfna5h
    • EG14210
    • Fin15
    • ICERE 1
    • ICERE-1
    • Inversely correlated with estrogen receptor expression 1
    • Non-syndromic hearing impairment protein 5
    • Nonsyndromic hearing impairment protein
    see all
  • 組織特異性
    Expressed in cochlea. Low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta.
  • 関連疾患
    Defects in DFNA5 are the cause of deafness autosomal dominant type 5 (DFNA5) [MIM:600994]. DFNA5 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
  • 配列類似性
    Belongs to the gasdermin family.
  • Information by UniProt

画像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116824 at approximately 80.63 kDa.

参考文献

ab116824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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