Recombinant Human delta 1 Catenin protein (ab114472)

製品の概要

  • 製品名Recombinant Human delta 1 Catenin protein
  • タンパク質長Protein fragment

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号Q96FS1
    • 生物種Human
    • 配列WGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKS DKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNKTLDRSGDLGDMEPL KGTTPLMQKI
    • 分子量38 kDa including tags
    • 領域721 to 830

特性

Our Abpromise guarantee covers the use of ab114472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    ELISA

    SDS-PAGE

    Western blot

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    ab114472 is best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • Cadherin associated Src substrate
    • Cadherin-associated Src substrate
    • CAS
    • Catenin (cadherin associated protein) delta 1
    • Catenin delta
    • Catenin delta 1
    • Catenin delta-1
    • CTND1_HUMAN
    • CTNND
    • CTNND 1
    • CTNND1
    • KIAA0384
    • p120
    • P120 CAS
    • p120 catenin
    • P120 CTN
    • p120(cas)
    • p120(ctn)
    • P120CAS
    • P120CTN
    see all
  • 機能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
  • 組織特異性Expressed in vascular endothelium.
  • 配列類似性Belongs to the beta-catenin family.
    Contains 10 ARM repeats.
  • ドメインA possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
  • 翻訳後修飾Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
  • 細胞内局在Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
  • Information by UniProt

Recombinant Human delta 1 Catenin protein 画像

  • ab114472 analysed on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human delta 1 Catenin protein (ab114472) 使用論文

ab114472 has not yet been referenced specifically in any publications.

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