製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus
  • アミノ酸配列
    • アクセッション番号Q16832
    • 生物種Human
    • 分子量70 kDa including tags
    • 領域467 to 855

特性

Our Abpromise guarantee covers the use of ab96401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性The specific activity was determined to be 48 nmol/min/mg.
  • アプリケーション

    SDS-PAGE

    Functional Studies

  • 精製度 90 % .
    Purity was determined to be >90% by densitometry.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 別名
    • CD167 antigen-like family member B
    • CD167b
    • CD167b antigen
    • Cell migration inducing protein 20
    • DDR 2
    • DDR2
    • DDR2_HUMAN
    • Discoidin domain containing receptor 2
    • Discoidin domain receptor 2
    • Discoidin domain receptor family member 2
    • discoidin domain receptor tyrosine kinase 2
    • Discoidin domain-containing receptor 2
    • discoidin domain-containing receptor tyrosine kinase 2
    • Hydroxyaryl protein kinase
    • MIG20a
    • Migration inducing gene 16 protein
    • Neurotrophic tyrosine kinase
    • Neurotrophic tyrosine kinase receptor related 3
    • NTRKR 3
    • NTRKR3
    • Receptor protein tyrosine kinase TKT
    • Receptor protein-tyrosine kinase TKT
    • Receptor related 3
    • receptor-related 3
    • TKT
    • TYRO 10
    • TYRO10
    • Tyrosine kinase receptor related to neurotrophic TRK
    • Tyrosine protein kinase TYRO 10
    • Tyrosine protein kinase TYRO10
    • Tyrosine-protein kinase TYRO10
    • Tyrosylprotein kinase
    see all
  • 機能This tyrosine kinase receptor for fibrillar collagen mediates fibroblast migration and proliferation. Contributes to cutaneous wound healing.
  • 組織特異性The major 10 kDa transcript is expressed in high levels in heart and lung, less in brain, placenta, liver, skeletal muscle, pancreas, and kidney.
  • 関連疾患Defects in DDR2 are the cause of spondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL) [MIM:271665]. A bone disease characterized by short-limbed dwarfism, a narrow chest with pectus excavatum, brachydactyly in the hands and feet, a characteristic craniofacial appearance and premature calcifications. The radiological findings are distinctive and comprise short long bones throughout the skeleton with striking epiphyses that are stippled, flattened and fragmented and flared, irregular metaphyses. Platyspondyly in the spine with wide intervertebral spaces is observed and some vertebral bodies are pear-shaped with central humps, anterior protrusions and posterior scalloping.
  • 配列類似性Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 1 F5/8 type C domain.
    Contains 1 protein kinase domain.
  • 細胞内局在Membrane.
  • Information by UniProt

Recombinant human DDR2 protein 画像

  • Kinase Assay demonstrating specific activity of ab96401.
  • SDS-PAGE showing ab96401 at approximately 70kDa.

Recombinant human DDR2 protein (ab96401) 使用論文

ab96401 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"