製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号Q7Z4W1
    • 生物種Human
    • 配列MGSSHHHHHH SSGLVPRGSH MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC
    • 分子量28 kDa including tags
    • 領域1 to 244
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab117694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab117694 is purified by proprietary chromatographic techniques
  • 製品の状態Liquid
  • 備考Please prevent freeze thaw cycles.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Store under Desiccating conditions.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 0.29% Sodium chloride, 20% Glycerol

関連情報

  • 別名
    • Carbonyl reductase 2
    • Carbonyl reductase II
    • DCR
    • Dcxr
    • DCXR_HUMAN
    • Dicarbonyl L xylulose reductase
    • Dicarbonyl/ L xylulose reductase
    • Dicarbonyl/L-xylulose reductase
    • HCR2
    • HCRII
    • Human carbonyl reductase 2
    • kiDCR
    • Kidney dicarbonyl reductase
    • L xylulose reductase
    • L-xylulose reductase
    • P34H
    • PNTSU
    • SDR20C1
    • Short chain dehydrogenase/reductase family 20C member 1
    • Sperm surface protein P34H
    • XR
    see all
  • 機能Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
  • 組織特異性Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
  • 関連疾患Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
  • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • 細胞内局在Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
  • Information by UniProt

Recombinant Human DCXR protein (ab117694) 使用論文

ab117694 has not yet been referenced specifically in any publications.

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